Human 3D Blood-Vessel-On-a-Chip Model Shows Cell Migration for Fibrotic Diseases AM Software
A team of scientists at the Wyss Institute at Harvard University and Boston University has created a 3D blood-vessel-on-a-chip model to investigate endothelial barrier failure, and found that inflammation disrupts the connections between endothelial cells and mural cells, causing the mural cells to retract or even detach from their usual position surrounding blood vessels and leading to further leakage.